Sickle-cell Anaemia, Sickle-cell Thalassaemia, Sickle-cell Haemoglobin C Disease, and Asymptomatic Haemoglobin C Thalassaemia in one Ghanaian Family

摘要

A Ghanaian family is described in which a sickle-cell haemoglobin C man married to a sickle-cell thalassaemia woman produced 12 children (eight alive). Four children have sickle-cell anaemia, two sickle-cell haemoglobin C disease, one has sickle-cell thalassaemia, and one is asymptomatic haemoglobin C thalassaemia.